Max it out. The only difference it makes is how long it takes to encode the file. In an extremely simplistic way, the encoder is trying multiple methods to make each chunk of data as small as possible. The higher the level of compression, the more tries it makes. This results in a smaller file, but the decoding time is not affected at all so there is no downside other than a slightly longer encoding time when the file is created.
Home Desk ~ MB 3.3 Portable • Questyle CMA400i (ASIO) • Sennheiser HD 660S (balanced) / Audeze EL-8 Closed Back / Fostex TR-X00 Ebony • Teac AI-101DA • Jamo C93 + Dayton Audio SUB-1000
Work Desk ~ MB 3.3 Portable / Tidal • SMSL SU-8 v2 • Nobsound NS-05P • THX AAA 789 • Sennheiser HD 58X (balanced)
OTG ~ FiiO M11 • Audiofly AF180 / B&O H6