This is my unexciting, somewhat unoriginal layout. I like everything like I had it when I used iTunes with the exception of the sidebar on the right which I enjoy especially when it is showing synchronized lyrics. I have my columns laid out just how I like them. You may notice that the Comment field may seem like a waste of space in this screenshot but I use it a lot, especially for show tunes and theme songs where I like to put which musical or show the song is from and what character sings it. Previously, before switching to MusicBee, I also used the Comment field to enter featured artists. Multiple artists tags and the Display Artist is one of the main reasons that I love MusicBee.
I am still looking for a theme that I want to use. I might try to customize my own, but for now I'll stick with the default.