Reinstall/update your audio drivers to start. Update MB to the latest version if you haven't already.
Are you using any effects on your audio devices like an EQ or something? If you open the properties of each audio device, open the enhancements tab, and check disable all enhancements, does that resolve the issue?
Another possibility, if you are using ASIO or WASAPI, does DirectSound resolve the issue? Personally, I've got one DAC that stutters with WASAPI and another that stutters with ASIO, but both work fine with DirectSound or the other exclusive option.
Home Desk ~ MB 3.3 Portable • Questyle CMA400i (ASIO) • Sennheiser HD 660S (balanced) / Audeze EL-8 Closed Back / Fostex TR-X00 Ebony • Teac AI-101DA • Jamo C93 + Dayton Audio SUB-1000
Work Desk ~ MB 3.3 Portable / Tidal • SMSL SU-8 v2 • Nobsound NS-05P • THX AAA 789 • Sennheiser HD 58X (balanced)
OTG ~ FiiO M11 • Audiofly AF180 / B&O H6