Possible I found the settings outside the MusicBee user folder (with playlists, podcasts etc.) here:
C:\Dokumente und Einstellungen\Markus\Anwendungsdaten\MusicBee
So next time when MusicBee lost my settings I will overwrite this files with the backup? And doesn't chance anything in my MusicBee folder (with playlists, podcasts etc.)?
But why does MusicBee starts simply with an factory reset when something gets wrong? Overwrites the complete hard work of the own settings without any chance to say no.