Sorry but I don't like the design in the initial post at all
For example, regarding the Album Artists list on the left, the circular artist images take up too much room and are unneccesary. It only displays 13 artists at one time, which could mean alot of scrolling when browsing.
The preview posted here
http://getmusicbee.com/forum/index.php?topic=14941.msg89396#msg89396 does not leave enough screen width to display the tracks. The more tag columns that can be visible the better as it allows more detail to be seen about each individual track such as title/album/artist/genre/bitrate/extension/year/rating/length etc. It also allows for easier sorting by clicking on the relevant column header.
Currently I like to use the column browsers to filter my music - mostly Genre and Artist, sometimes Album. It's great how they can be used together, but I don't see how that would work in the new skin.
Like dusty-2011 above, I only like the Classic skin in the current MusicBee. It's simple and elegant, easy to read and can display alot of information. There's no need to waste time making massive changes!
I guess I don't mind if the current left navigator panel has to go as long as playlists can still be reached in one click. I don't pay much attention to the Now Playing panel.