Track Information in the main panel - called "now playing bar" has the same setup as Track Information in the right sidebar.
I have "Do not display artwork" chosen and it works in the right sidebar track information panel.
But there is always a picture shown to the left of the track information in the "now playing bar" of the main panel. I would prefer to be able to turn off that artwork. I'm also somewhat curious about where that artwork is coming from - it usually bears no relation to the music for me.